Recombinant Human CD52 Protein, C-Fc-Avi tagged, Biotinylated

• Cat.No.: CD52-21H
• Product Overview: Biotinylated Recombinant Human CAMPATH-1 Antigen is produced by our Mammalian expression system and the target gene encoding Gly25-Ser36 is expressed with a Fc, Avi tag at the C-terminus.

Specification

• Species: Human
• Source: Human Cells
• Tag: Avi&Fc
• Protein Length: Gly25-Ser36
• Description: CD52, also known as CAMPATH-1 antigen, HE5, and gp20, is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocycte-derived dendritic cells, eosinophils, and neutrophils, as well as on mature spermatozoa and epithelial cells lining the male genital tract. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.
• Endotoxin: Less than 0.1 ng/μg (1 EU/μg)
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Shipping: Ambient

Gene Information

• Gene Name: CD52 CD52 molecule [ Homo sapiens (human) ]
• Official Symbol: CD52
• Synonyms: CAMPATH-1 antigen; CAMPATH-1; CD52 antigen; CD52 molecule; CD52; CDw52; Epididymal secretory protein E5; He5; HEL-S-171mP; Human epididymis-specific protein 5
• Gene ID: 1043
• mRNA Refseq: NM_001803
• Protein Refseq: NP_001794
• MIM: 114280
• UniProt ID: P31358