Recombinant Human CD44 Molecule (Indian Blood Group)

• Cat.No.: CD44-1412H
• Product Overview: Recombinant human CD44 protein is produced from cell culture supernatants.

Specification

• Species: Human
• Tag: Non
• Description: CD44 is a cell-surface glycoprotein that plays a role in cell-cell interactions, cell adhesion and migration. CD44 is a receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. CD44 participates in a wide variety of cellular functions such as lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. CD44 and CD49d are putative activity markers and CD44 a potential novel therapeutic target in multiple sclerosis. Increased CD44 antigen is associated with relapses in non-small cell lung cancers.
• Presentation: It is presented in cell culture supernatants containing 1%FCS, 0.2mM Natriumbutyrat, penicillin, streptomycin und amphotericin B.
• Concentration: 11.5 µg/ml.
• Storage: It is shipped at -20°C. Store at -20°C.

Gene Information

• Gene Name: CD44 CD44 molecule (Indian blood group) [ Homo sapiens ]
• Synonyms: CD44; CD44 molecule (Indian blood group); IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; MUTCH-I; ECMR-III; MGC10468; CD44 antigen; CD44 antigen (homing function and Indian blood group system); CDW44 antigen; GP90 lymphocyte homing/adhesion receptor; Hermes antigen; antigen gp90 homing receptor; cell adhesion molecule; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; extracellular matrix receptor-III; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; homing function and Indian blood group system; hyaluronate receptor; phagocytic glycoprotein I
• Gene ID: 960
• mRNA Refseq: NM_000610
• Protein Refseq: NP_000601
• MIM: 07269
• UniProt ID: P16070
• Chromosome Location: 11p13
• Pathway: ECM-receptor interaction; Hematopoietic cell lineage
• Function: collagen binding; hyaluronic acid binding; phosphoprotein binding; receptor activity