Recombinant Human CD4 Protein, His & Avi-tagged
Cat.No. : | CD4-24H |
Product Overview : | Biotinylated Human CD4, His Tag is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Pro 396. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The single lysine residue in the Avitag is enzymatically labeled with biotin. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | HEK293 |
Tag : | Avi&His |
Protein Length : | 26-396 a.a. |
Description : | T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients. |
Predicted N Terminal : | Lys 26 |
Molecular Mass : | The protein has a calculated MW of 45.0 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at: 4-8 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. |
Gene Name | CD4 |
Official Symbol | CD4 CD4 molecule [ Homo sapiens (human) ] |
Synonyms | CD4; CD4mut; LEU3; CD4 molecule; T-cell surface glycoprotein CD4; CD4 antigen (p55); CD4 receptor; T-cell surface antigen T4/Leu-3 |
Gene ID | 920 |
mRNA Refseq | NM_000616 |
Protein Refseq | NP_000607 |
MIM | 186940 |
UniProt ID | P01730 |
◆ Cell & Tissue Lysates | ||
CD4-947CCL | Recombinant Cynomolgus CD4 cell lysate | +Inquiry |
CD4-2580MCL | Recombinant Mouse CD4 cell lysate | +Inquiry |
CD4-1905HCL | Recombinant Human CD4 cell lysate | +Inquiry |
CD4-1865FCL | Recombinant Ferret CD4 cell lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All CD4 Products
Required fields are marked with *
My Review for All CD4 Products
Required fields are marked with *
0
Inquiry Basket