Recombinant Human CD3E & CD3G Protein, Fc-tagged

• Cat.No.: CD3E & CD3G-145H
• Product Overview: Human CD3 epsilon & CD3 gamma Heterodimer Protein is expressed from mammalian with a Fc Tag at the C-terminal. It contains Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G).

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G)
• Description: T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Endotoxin: Less than 0.01 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE. > 95% as determined by HPLC.
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: CD3E CD3e molecule [ Homo sapiens (human) ]
• Official Symbol: CD3E & CD3G
• Synonyms: CD3E; CD3G
• Gene ID: 916
• mRNA Refseq: NM_000733.4
• Protein Refseq: NP_000724.1
• MIM: 186830
• UniProt ID: P07766