Recombinant Human CD177 protein, His-tagged

• Cat.No.: CD177-7807H
• Product Overview: Recombinant Human CD177 (Leu22-Gly407) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: Leu22-Gly407
• Description: CD antigen CD177 is also known as Polycythemia rubra vera protein 1 (PRV-1), Human neutrophil alloantigen 2a, NB1 glycoprotein, is a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein. CD177 contains two UPAR/Ly6 domains. CD177 is highly expressed in normal bone marrow and weakly expressed in fetal liver. PECAM-1 is a binding partner of CD177.
• Predicted N Terminal: Leu22
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 43.2 kDa. The protein migrates as 50-57 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >90% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: CD177
• Official Symbol: CD177
• Synonyms: CD177; CD177 molecule; CD177 antigen; HNA2A; NB1; polycythemia rubra vera 1; PRV1; NB1 glycoprotein; cell surface receptor; human neutrophil alloantigen 2a; polycythemia rubra vera protein 1; PRV-1; HNA-2a; NB1 GP
• Gene ID: 57126
• mRNA Refseq: NM_020406
• Protein Refseq: NP_065139
• MIM: 162860
• UniProt ID: Q8N6Q3