Recombinant Human CD160 Protein, His-Tagged
| Cat.No. : | CD160-01H |
| Product Overview : | Recombinant Human CD160 Protein, His-Tagged was expressed in Baculovirus cell line |
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| Description : | CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. |
| Source : | Baculovirus |
| Species : | Human |
| Tag : | His |
| Form : | Liquid |
| Molecular Mass : | 15.9 kDa |
| Protein length : | 142aa |
| Endotoxin : | < 1 EU per 1ug of protein (determined by LAL method) |
| Purity : | > 90% by SDS-PAGE |
| Applications : | SDS-PAGE |
| Usage : | For research use only. This product is not intended or approved for human, diagnostics or veterinary use. |
| Storage : | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles. |
| Concentration : | 0.25mg/ml (determined by absorbance at 280nm) |
| Storage Buffer : | Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
| Gene Name | CD160 CD160 molecule [ Homo sapiens (human) ] |
| Official Symbol | CD160 |
| Synonyms | CD160 antigen, CD160, BY55, NK1, NK28 |
| Gene ID | 11126 |
| mRNA Refseq | NM_007053.4 |
| Protein Refseq | NP_008984.1 |
| MIM | 604463 |
| UniProt ID | O95971 |
Not For Human Consumption!
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