Recombinant Human CCL23 Protein, His-tagged

• Cat.No.: CCL23-151H
• Product Overview: Recombinant Human C-C motif chemokine ligand 23(CCL23), transcript variant CKbeta8(NM_145898), with a His tag.

Specification

• Description: This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013].
• Source: Human Cells
• Species: Human
• Tag: His
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.82, without any preservatives.
• Molecular Mass: 11.3 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: CCL23 chemokine (C-C motif) ligand 23 [ Homo sapiens ]
• Official Symbol: CCL23
• Synonyms: CCL23; chemokine (C-C motif) ligand 23; SCYA23, small inducible cytokine subfamily A (Cys Cys), member 23; C-C motif chemokine 23; Ckb 8; CKb8; MIP 3; MPIF 1; hmrp-2a; C6 beta-chemokine; small-inducible cytokine A23; macrophage inflammatory protein 3; myeloid progenitor inhibitory factor 1; small inducible cytokine subfamily A (Cys-Cys), member 23; MIP3; Ckb-8; MIP-3; MPIF-1; SCYA23; Ckb-8-1; CK-BETA-8
• Gene ID: 6368
• mRNA Refseq: NM_005064
• Protein Refseq: NP_005055
• MIM: 602494
• UniProt ID: P55773