Recombinant Human CCL2 protein, His-Avi-tagged

• Cat.No.: CCL2-500H
• Product Overview: Recombinant Human MCP-1/CCL2 is expressed from mammalian with a His Tag and Avi Tag at the C-terminal. It contains Gln24-Thr99.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: Gln24-Thr99
• Description: Monocyte chemotactic protein-1 (MCP-1) (also referred to as chemokine (C-C motif) ligand 2 (CCL2) is expressed by mainly inflammatory cells and endothelial cells. MCP-1 has been reported to play an important role in the pathogenesis of atherosclerosis and considerable evidence supports that the monocyte containing MCPs and macrophage influences the growth of other cell types within the atherosclerotic lesion. This review will focus on the general structure features of MCP-1 and its role in atherosclerosis.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 11.5 kDa.Due to glycosylation, the protein migrates to 15-20 KDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 1 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: CCL2
• Official Symbol: CCL2
• Synonyms: C-C motif chemokine 2, CCL2, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor
• Gene ID: 6347
• mRNA Refseq: NM_002982.4
• Protein Refseq: NP_002973.1
• MIM: 158105
• UniProt ID: P13500