Recombinant Human CCDC104, GST-tagged

• Cat.No.: CCDC104-10781H
• Product Overview: Recombinant Human CCDC104 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-342a.a.
• Description: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CCDC104 coiled-coil domain containing 104 [ Homo sapiens ]
• Official Symbol: CCDC104
• Synonyms: CCDC104; coiled-coil domain containing 104; coiled-coil domain-containing protein 104; MGC15407
• Gene ID: 112942
• mRNA Refseq: NM_080667
• Protein Refseq: NP_542398
• UniProt ID: Q96G28
• Chromosome Location: 2p16.1