Recombinant Human CBLC Protein, FLAG-tagged

• Cat.No.: CBLC-443H
• Product Overview: Recombinant human CBLC Protein (a.a. 11-404) with N-terminal FLAG-tag, was expressed in a HEK293 expression system.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag
• Protein Length: 11-404 a.a.
• Description: This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Form: Aqueous buffer solution.
• Molecular Mass: 45 kDa
• Stability: At least 6 months at –80 centigrade.
• Storage Buffer: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% Glycerol and 100 μg/mL FLAG peptide.

Gene Information

• Gene Name: CBLC Cbl proto-oncogene C [ Homo sapiens (human) ]
• Official Symbol: CBLC
• Synonyms: CBLC; Cbl proto-oncogene C; CBL-3; RNF57; CBL-SL; E3 ubiquitin-protein ligase CBL-C; Cas-Br-M (murine) ecotropic retroviral transforming sequence c; Cas-Br-M (murine) ectropic retroviral transforming sequence c; Cbl proto-oncogene C, E3 ubiquitin protein ligase; Cbl proto-oncogene, E3 ubiquitin protein ligase C; RING finger protein 57; RING-type E3 ubiquitin transferase CBL-C; SH3-binding protein CBL-3; SH3-binding protein CBL-C; signal transduction protein CBL-C; EC 2.3.2.27
• Gene ID: 23624
• mRNA Refseq: NM_012116
• Protein Refseq: NP_036248
• MIM: 608453
• UniProt ID: Q9UlV8