Recombinant Human capping protein (actin filament) muscle Z-line, alpha 2, His-tagged

• Cat.No.: CAPZA2-273H
• Product Overview: CAPZA2, 1-286aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-286 a.a.
• Description: CAPZA2 is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end. Recombinant human CAPZA2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M UREA
• Molecular Mass: 35.3 kDa (309aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMADLEEQ LSDEEKVRIA AKFIIHAPPG EFNEVFNDVR LLLNNDNLLR EGAAHAFAQY NLDQFTPVKI EGYEDQVLIT EHGDLGNGKF LDPKNRICFK FDHLRKEATD PRPCEVENAV ESWRTSVETA LRAYVKEHYP NGVCTVYGKK IDGQQTIIAC IESHQFQAKN FWNGRWRSEW KFTITPSTTQ VVGILKIQVH YYEDGNVQLV SHKDIQDSLT VSNEVQTAKE FIKIVEAAEN EYQTAISENY QTMSDTTFKA LRRQLPVTRT KIDWNKILSY KIGKEMQNA
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 [ Homo sapiens ]
• Official Symbol: CAPZA2
• Synonyms: CAPZA2; capping protein (actin filament) muscle Z-line, alpha 2; F-actin-capping protein subunit alpha-2; CAPPA2; CAPZ; F actin capping protein alpha 2 subunit; capZ alpha-2; F-actin capping protein alpha-2 subunit
• Gene ID: 830
• mRNA Refseq: NM_006136
• Protein Refseq: NP_006127
• MIM: 601571
• UniProt ID: P47755
• Chromosome Location: 7q31.2-q31.3
• Pathway: Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem
• Function: actin binding