Recombinant Human cAMP-Dependent Protein Kinase Inhibitor Beta, His-tagged

• Cat.No.: PKIB-972H
• Product Overview: Recombinant human PKIB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography(1-78 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: PKIB, also known as cAMP-dependent protein kinase inhibitor beta, is a member of the cAMP-dependent protein kinase inhibitor family. This protein may interact with the catalytic subunit of cAMP-dependent protein kinase and act as a competitive inhibitor. At least three alternatively spliced transcript variants encoding the same protein have been reported.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
• Molecular Weight: 10.6 kDa (98aa) confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher)
• Purity: > 95% by SDS - PAGE
• Concentration: 1.0 mg/ml (determined by BCA assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSHMRTDSSKMTD VESGVANFASSARAGRRNAL PDIQSSAATD GTSDLPLKLE ALSVKEDAKE KDEKTTQDQLEKPQNEEK
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta [Homo sapiens]
• Synonyms: PKIB; RP11-95G17.1;FLJ23817; PRKACN2; PKI-beta;OTTHUMP00000017115;cAMP-dependent protein kinase inhibitor2; cAMP-dependent protein kinase inhibitor beta; protein kinase (cAMP-dependent, catalytic) inhibitor beta; OTTHUMP00000017116; OTTHUMP00000017117
• Gene ID: 5570
• mRNA Refseq: NM_032471
• Protein Refseq: NP_115860
• MIM: 606914
• UniProt ID: Q9C010
• Chromosome Location: 6q22.31
• Function: cAMP-dependent protein kinase inhibitor activity; protein kinase inhibitor activity