Recombinant Human CAMK2G, GST-tagged

• Cat.No.: CAMK2G-10684H
• Product Overview: Recombinant Human CAMK2G protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-310a.a.
• Description: The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CAMK2G calcium/calmodulin-dependent protein kinase II gamma [ Homo sapiens ]
• Official Symbol: CAMK2G
• Synonyms: CAMK2G; calcium/calmodulin-dependent protein kinase II gamma; calcium/calmodulin dependent protein kinase (CaM kinase) II gamma , CAMKG; calcium/calmodulin-dependent protein kinase type II subunit gamma; caMK-II subunit gamma; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; CAMK; CAMKG; CAMK-II; FLJ16043; MGC26678
• Gene ID: 818
• mRNA Refseq: NM_001204492
• Protein Refseq: NP_001191421
• MIM: 602123
• UniProt ID: Q13555
• Chromosome Location: 10q22
• Pathway: Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; BCR signaling pathway, organism-specific biosystem; CREB phosphorylation through the activation of CaMKII, organism-specific biosystem; CREB phosphorylation through the activation of Ras, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem
• Function: ATP binding; ATP binding; calcium-dependent protein serine/threonine phosphatase activity; calmodulin binding; calmodulin binding; calmodulin-dependent protein kinase activity; calmodulin-dependent protein kinase activity; nucleotide binding