Recombinant Human CALB2, His-tagged

• Cat.No.: CALB2-27214TH
• Product Overview: Recombinant full length Human Calretinin , with N terminal His-tag; 291aa, MWt 33.7kDa inclusive of tag.

Specification

• Description: This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants.
• Protein length: 271 amino acids
• Conjugation: HIS
• Molecular Weight: 33.700kDa
• Source: E. coli
• Tissue specificity: Brain.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, pH 8
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAGPQQQPPY LHLAELTASQ FLEIWKHFDA DGNGYIEGKE LENFFQELEK ARKGSGMMSK SDNFGEKMKE FMQKYDKNSD GKIEMAELAQ ILPTEENFLL CFRQHVGSST EFMEAWRKYD TDRSGYIEAN ELKGFLSDLL KKANRPYDEP KLQEYTQTIL RMFDLNGDGK LGLSEMSRLL PVQENFLLKF QGMKLTSEEF NAIFTFYDKD RSGYIDEHEL DALLKDLYEK NKKEMNIQQL TNYRKSVMSL AEAGKLYRKD LEIVLCSEPP M
• Sequence Similarities: Belongs to the calbindin family.Contains 6 EF-hand domains.

Gene Information

• Gene Name: CALB2 calbindin 2 [ Homo sapiens ]
• Official Symbol: CALB2
• Synonyms: CALB2; calbindin 2; calbindin 2, 29kDa (calretinin); calretinin; CAL2
• Gene ID: 794
• mRNA Refseq: NM_001740
• Protein Refseq: NP_001731
• MIM: 114051
• Uniprot ID: P22676
• Chromosome Location: 16q22.2
• Function: calcium ion binding