Recombinant Human CACYBP, His-tagged

• Cat.No.: CACYBP-29815TH
• Product Overview: Recombinant full length protein, corresponding to amino acids 1-228 of Human SIAH Interacting Protein with an N terminal His tag. Predicted MWt: 27 kDa.

Specification

• Description: The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 100 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MASEELQKDLEEVKVLLEKATRKRVRDALTAEKSKIETEI KNKMQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNY GWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLL VKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILC RKKVENTRWDYLTQVEKECKEKEKPSYDTETDPSEGLMNV LKKIYEDGDDDMKRTINKAWVESREKQAKGDTEF
• Protein length: 1-228 a.a.
• Full Length: Full L.

Gene Information

• Gene Name: CACYBP calcyclin binding protein [ Homo sapiens ]
• Official Symbol: CACYBP
• Synonyms: CACYBP; calcyclin binding protein; calcyclin-binding protein; S100A6BP; SIP
• Gene ID: 27101
• mRNA Refseq: NM_001007214
• Protein Refseq: NP_001007215
• MIM: 606186
• Uniprot ID: Q9HB71
• Chromosome Location: 1q24-q25
• Pathway: Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem
• Function: protein binding; protein homodimerization activity