Recombinant Human CA9 Protein, His\Avi-tagged

• Cat.No.: CA9-192H
• Product Overview: Biotinylated Recombinant Human Carbonic Anhydrase 9 is produced by our Mammalian expression system and the target gene encoding Gln38-Asp414 is expressed with a 6His, Avi tag at the Cterminus.

Specification

• Species: Human
• Source: Human Cells
• Tag: His&Avi
• ProteinLength: 38-414 a.a.
• Description: Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Appears to be a novel specific biomarker for a cervical neoplasia.
• Form: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Molecular Mass: Predicted Molecular Weight: 43.6kDa
  Apparent Molecular Weight: 60kDa, reducing conditions.
• AA Sequence: Gln38-Asp414
• Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
• Purity: >95%
• Storage: Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
  Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
• Reconstitution: It is not recommended to reconstitute to a concentration less than 100μg/ml.
  Dissolve the lyophilized protein in distilled water.
  Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Quality Statement: Purity: greater than 95% as determined by reducing SDS-PAGE.
• Shipping: The product is shipped at ambient temperature.
  Upon receipt, store it immediately at the temperature listed below.

Gene Information

• Gene Name: CA9 carbonic anhydrase 9 [ Homo sapiens (human) ]
• Official Symbol: CA9
• Synonyms: CA9; CA-IX; Carbonic Anhydrase IX; Carbonate dehydratase IX; G250; MN; P54/58N; RCC; RCC-associated protein G250; CAIX
• Gene ID: 768
• mRNA Refseq: NM_001216.3
• Protein Refseq: NP_001207.2
• MIM: 603179
• UniProt ID: Q16790