Recombinant Human C9, His-tagged

• Cat.No.: C9-5126H
• Product Overview: Recombinant human C9 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Description: C9 is the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
• Molecular Mass: 63.4 kDa (561aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSQYTTSYD PELTESSGSA SHIDCRMSPW SEWSQCDPCL RQMFRSRSIE VFGQFNGKRC TDAVGDRRQC VPTEPCEDAE DDCGNDFQCS TGRCIKMRLR CNGDNDCGDF SDEDDCESEP RPPCRDRVVE ESELARTAGY GINILGMDPL STPFDNEFYN GLCNRDRDGN TLTYYRRPWN VASLIYETKG EKNFRTEHYE EQIEAFKSII QEKTSNFNAA ISLKFTPTET NKAEQCCEET ASSISLHGKG SFRFSYSKNE TYQLFLSYSS KKEKMFLHVK GEIHLGRFVM RNRDVVLTTT FVDDIKALPT TYEKGEYFAF LETYGTHYSS SGSLGGLYEL IYVLDKASMK RKGVELKDIK RCLGYHLDVS LAFSEISVGA EFNKDDCVKR GEGRAVNITS ENLIDDVVSL IRGGTRKYAF ELKEKLLRGT VIDVTDFVNW ASSINDAPVL ISQKLSPIYN LVPVKMKNAH LKKQNLERAI EDYINEFSVR KCHTCQNGGT VILMDGKCLC ACPFKFEGIA CEISKQKISE GLPALEFPNE K
• Purity: >80% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: C9 complement component 9 [ Homo sapiens ]
• Official Symbol: C9
• Synonyms: C9; complement component 9; complement component C9
• Gene ID: 735
• mRNA Refseq: NM_001737
• Protein Refseq: NP_001728
• MIM: 120940
• UniProt ID: P02748
• Chromosome Location: 5p14-p12
• Pathway: Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Complement Activation, Classical Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem