Recombinant Human C1QBP protein, His-tagged

• Cat.No.: C1QBP-6877H
• Product Overview: Recombinant Human C1QBP (His75-Gln282) protein was fused to His-tag at C-terminus and expressed in E.coli.

Specification

• Description: Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP), a member of the MAM33 family, is also known as ASF/SF2-associated protein p32, glycoprotein gC1qBP (C1qBP), mitochondrial matrix protein p32 and hyaluronan-binding protein 1, which is a homotrimer that contains three monomers forming a donut-shaped structure with an unusually asymmetric charge distribution on the surface. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. C1QBP has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. Furthermore, C1QBP has been shown to interact with Protein kinase D1, BAT2, PRKCD, PKC alpha and Protein kinase Mζ .
• Source: E.coli
• Species: Human
• Tag: His
• Predicted N Terminal: His75
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 24.6 kDa. The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE).
• Protein length: His75-Gln282
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: C1QBP
• Official Symbol: C1QBP
• Synonyms: C1QBP; complement component 1, q subcomponent binding protein; HABP1; complement component 1 Q subcomponent-binding protein, mitochondrial; C1q globular domain binding protein; gC1Q R; gC1qR; hyaluronan binding protein 1; p32; SF2p32; splicing factor SF2 associated protein; p33; glycoprotein gC1qBP; hyaluronan-binding protein 1; mitochondrial matrix protein p32; C1q globular domain-binding protein; splicing factor SF2-associated protein; GC1QBP; gC1Q-R
• Gene ID: 708
• mRNA Refseq: NM_001212
• Protein Refseq: NP_001203
• MIM: 601269
• UniProt ID: Q07021