Recombinant Human C1D, His-tagged

• Cat.No.: C1D-7636H
• Product Overview: Recombinant human C1D protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 1-141aa
• Description: Nuclear nucleic acid-binding protein C1D, also known as C1D, plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3"-5" end processing of the 5.8S rRNA; this function may include MPHOSPH6. This protein can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. This protein can induce apoptosis in a p53/TP53 dependent manner.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
• Molecular Mass: 18.4kDa (164aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAGEEIN EDYPVEIHEY LSAFENSIGA VDEMLKTMMS VSRNELLQKL DPLEQAKVDL VSAYTLNSMF WVYLATQGVN PKEHPVKQEL ERIRVYMNRV KEITDKKKAG KLDRGAASRF VKNALWEPKS KNASKVANKG KSKS
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: C1D C1D nuclear receptor corepressor [ Homo sapiens ]
• Official Symbol: C1D
• Synonyms: C1D; C1D nuclear receptor corepressor; C1D nuclear receptor co repressor; nuclear nucleic acid-binding protein C1D; LRP1; small unique nuclear receptor co repressor; SUN CoR; SUNCOR; C1D DNA-binding protein; nuclear DNA-binding protein; C1D nuclear receptor co-repressor; small unique nuclear receptor corepressor; small unique nuclear receptor co-repressor; hC1D; SUN-CoR; MGC12261; MGC14659
• Gene ID: 10438
• mRNA Refseq: NM_173177
• Protein Refseq: NP_775269
• MIM: 606997
• UniProt ID: Q13901
• Chromosome Location: 2p13-p12
• Pathway: RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem
• Function: DNA binding; RNA binding; ligand-dependent nuclear receptor binding; protein binding; transcription corepressor activity