Recombinant Human BTN3A1 protein, Fc-tagged
Cat.No. : | BTN3A1-736H |
Product Overview : | Recombinant Human BTN3A1 (Gln30-Gly254) protein was fused to human IgG1 Fc tag at C-terminus and expressed in human 293 cells (HEK293). |
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Species : | Human |
Source : | HEK293 |
Tag : | Fc |
Protein Length : | Gln30-Gly254 |
Description : | Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. |
Predicted N Terminal : | Gln30 |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 50.8 kDa. As a result of glycosylation, the protein migrates as 58-65 kDa under reducing (R) condition, and 120 kDa under non-reducing (NR) condition (SDS-PAGE). |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name | BTN3A1 |
Official Symbol | BTN3A1 |
Synonyms | BTN3A1; butyrophilin, subfamily 3, member A1; butyrophilin subfamily 3 member A1; BT3.1; BTF5; CD277; dJ45P21.3 (butyrophilin, subfamily 3, member A1); MGC141880 |
Gene ID | 11119 |
mRNA Refseq | NM_001145008 |
Protein Refseq | NP_001138480 |
MIM | 613593 |
UniProt ID | O00481 |
◆ Recombinant Proteins | ||
BTN3A1-1530HFL | Recombinant Full Length Human BTN3A1 Protein, C-Flag-tagged | +Inquiry |
BTN3A1-2331H | Recombinant Human BTN3A1 Protein (30-254 aa), His-tagged | +Inquiry |
BTN3A1-47HB | Recombinant Human BTN3A1 protein, His-tagged, Biotinylated | +Inquiry |
BTN3A1-737H | Recombinant Human BTN3A1 Protein, Fc-Avi-tagged, Biotinylated | +Inquiry |
BTN3A1-001H | Active Recombinant Human BTN3A1, MIgG2a Fc-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
BTN3A1-8386HCL | Recombinant Human BTN3A1 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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