Recombinant Human Biliverdin Reductase A

• Cat.No.: BLVRA-2508H
• Product Overview: Recombinant BLVRA protein was expressed in E. coli and purified by using conventional chromatography techniques. MW: 33.3 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 3-296aa
• Description: BLVRA, also known as biliverdin reductase A, belongs to the gfo/idh/mocA family. This protein is an enzyme that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond.
• Form: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol.
• Molecular Mass: 33.3 kDa (295aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
• AA Sequence: MAEPERKFGV VVVGVGRAGS VRMRDLRNPH PSSAFLNLIG FVSRRELGSI DGVQQISLED ALSSQEVEVA YICSESSSHE DYIRQFLNAG KHVLVEYPMT LSLAAAQELW ELAEQKGKVL HEEHVELLME EFAFLKKEVV GKDLLKGSLL FTAGPLEEER FGFPAFSGIS RLTWLVSLFG ELSLVSATLE ERKEDQYMKM TVCLETEKKS PLSWIEEKGP GLKRNRYLSF HFKSGSLENV PNVGVNKNIF LKDQNIFVQK LLGQFSEKEL AAEKKRILHC LGLAEEIQKY CCSRK
• Endotoxin: < 1.0 eu per 1 micogram of protein (determined by lal
• Purity: >90% by SDS-PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: BLVRA biliverdin reductase A [ Homo sapiens ]
• Official Symbol: BLVRA
• Synonyms: BLVRA; biliverdin reductase A; BLVR; BVR A; biliverdin-IX alpha-reductase; BVR; BVRA
• Gene ID: 644
• mRNA Refseq: NM_000712
• Protein Refseq: NP_000703
• MIM: 109750
• UniProt ID: P53004
• Chromosome Location: 7p14-cen
• Pathway: Heme degradation, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of porphyrins, organism-specific biosystem; Porphyrin and chlorophyll metabolism, organism-specific biosystem; Porphyrin and chlorophyll metabolism, conserved biosystem; heme degradation, organism-specific biosystem; heme degradation, conserved biosystem
• Function: biliverdin reductase activity; metal ion binding; nucleotide binding; oxidoreductase activity; zinc ion binding