Recombinant Human BDH2, His-tagged

• Cat.No.: BDH2-26100TH
• Product Overview: Recombinant full length Human BDH2 with an N terminal His tag; 265 amino acids with a predicted MWt 28.8 kDa including tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 245 amino acids
• Description: BDH2, also known as DHRS6, belongs to the short-chain dehydrogenases/reductases (SDR) family. This protein may play an important role in the peripheral utilization of 3-hydroxybutyrate.
• Conjugation: HIS
• Molecular Weight: 28.800kDa inclusive of tags
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL
• Sequence Similarities: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Gene Information

• Gene Name: BDH2 3-hydroxybutyrate dehydrogenase, type 2 [ Homo sapiens ]
• Official Symbol: BDH2
• Synonyms: BDH2; 3-hydroxybutyrate dehydrogenase, type 2; dehydrogenase/reductase (SDR family) member 6 , DHRS6; 3-hydroxybutyrate dehydrogenase type 2; FLJ13261; PRO20933; SDR15C1; short chain dehydrogenase/reductase family 15C; member 1; UCPA OR; UNQ6308
• Gene ID: 56898
• mRNA Refseq: NM_020139
• Protein Refseq: NP_064524
• Uniprot ID: Q9BUT1
• Chromosome Location: 4q24
• Pathway: Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Synthesis and degradation of ketone bodies, organism-specific biosystem; Synthesis and degradation of ketone bodies, conserved biosystem
• Function: 3-hydroxybutyrate dehydrogenase activity; NAD binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor