Recombinant Human BDH1 Protein, His-tagged

• Cat.No.: BDH1-137H
• Product Overview: Recombinant Human BDH1, transcript variant 3, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Supplied as a 0.2 µM filtered solution of 50mM Tris, 1mM DTT, pH 7.5
• Molecular Mass: 40.3kD
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMLATRLSRPLSRLPGKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFGFALAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSV
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining

Gene Information

• Gene Name: BDH1 3-hydroxybutyrate dehydrogenase, type 1 [ Homo sapiens ]
• Official Symbol: BDH1
• Synonyms: BDH1; 3-hydroxybutyrate dehydrogenase, type 1; 3 hydroxybutyrate dehydrogenase (heart, mitochondrial) , BDH; D-beta-hydroxybutyrate dehydrogenase, mitochondrial; SDR9C1; short chain dehydrogenase/reductase family 9C; member 1; (R)-3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase (heart, mitochondrial); short chain dehydrogenase/reductase family 9C, member 1; BDH; MGC2723; MGC4347; MGC9788
• Gene ID: 622
• mRNA Refseq: NM_203314
• Protein Refseq: NP_976059
• MIM: 603063
• UniProt ID: Q02338