Recombinant Human BCL2 Protein

• Cat.No.: BCL2-22H
• Product Overview: Recombinant Human BCL2 Protein without tag was expressed in E. coli.

Specification

• Description: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Molecular Mass: 24.7 kDa
• Purity: > 95% by SDS-PAGE
• Usage: For research purposes only (Inhibitor Screening, binding assay)
• Storage: Stable for 12 months at -80 centigrade, Avoid freeze/thaw cycles
• Storage Buffer: 25 mM Tris-HCl, 150 mM NaCl, 2 mM DTT, 10% Glycerol

Gene Information

• Gene Name: BCL2 B-cell CLL/lymphoma 2 [ Homo sapiens (human) ]
• Official Symbol: BCL2
• Synonyms: BCL2; B-cell CLL/lymphoma 2; apoptosis regulator Bcl-2; Bcl 2; PPP1R50; protein phosphatase 1; regulatory subunit 50; protein phosphatase 1, regulatory subunit 50; Bcl-2
• Gene ID: 596
• mRNA Refseq: NM_000633
• Protein Refseq: NP_000624
• MIM: 151430
• UniProt ID: P10415