Recombinant Human BCL2-Like 2, His-tagged

• Cat.No.: BCL2L2-1835H
• Product Overview: Recombinant human BCL2L2 fused to His-tag at N-terminus was expressed inE.coliand purified by using conventional chromatography techniques.MW = 20.9 kDa (192aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: BCL2-like protein 2, also known as BCL2L2, is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. BCL2L2 is an anti apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. It is required for normal sperm maturation.
• Form: Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 100mM NaCl, 10% glycerol.
• Purity: > 95% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MATPASAPDT RALVADFVGY KLRQKGYVCG AGPGEGPAAD PLHQAMRAAG DEFETRFRRT FSDLAAQLHVTPGSAQQRFT QVSDELFQGG PNWGRLVAFF VFGAALCAES VNKEMEPLVG QVQEWMVAYL ETRLADWIHS SGGWAEFTAL YGDGALEEARRLREGNWASV RT.
• Storage: can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: BCL2L2 BCL2-like 2 [ Homo sapiens ]
• Synonyms: BCL2-like 2; BCLW; BCL-W; KIAA0271; BCL2L2; BCL2-like 2 protein; apoptosis regulator BCL-W; Bcl2-L-2; Apoptosis regulator Bcl-W
• Gene ID: 599
• mRNA Refseq: NM_004050
• Protein Refseq: NP_004041
• MIM: 601931
• UniProt ID: Q92843
• Chromosome Location: 14q11.2-q12
• Function: protein binding