Recombinant Human ATP1B2, His-tagged

• Cat.No.: ATP1B2-15901H
• Product Overview: Recombinant human ATP1B2 protein, fused to His tag at N-terminus, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 68-290aa
• Description: ATP1B2 is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of the beta-2 subunit is not known. The protein is composed of three subunits: alpha (catalytic), beta and gamma.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M Urea
• Molecular Mass: 27.8 kDa (246aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSDHTPKYQ DRLATPGLMI RPKTENLDVI VNVSDTESWD QHVQKLNKFL EPYNDSIQAQ KNDVCRPGRY YEQPDNGVLN YPKRACQFNR TQLGNCSGIG DSTHYGYSTG QPCVFIKMNR VINFYAGANQ SMNVTCAGKR DEDAENLGNF VMFPANGNID LMYFPYYGKK FHVNYTQPLV AVKFLNVTPN VEVNVECRIN AANIATDDER DKFAGRVAFK LRINKT
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide [ Homo sapiens ]
• Official Symbol: ATP1B2
• Synonyms: ATP1B2; ATPase, Na+/K+ transporting, beta 2 polypeptide; sodium/potassium-transporting ATPase subunit beta-2; AMOG; adhesion molecule on glia; Na, K-ATPase beta-2 polypeptide; sodium/potassium-dependent ATPase beta-2 subunit; sodium/potassium-dependent ATPase subunit beta-2; sodium/potassium-transporting ATPase beta-2 chain
• Gene ID: 482
• mRNA Refseq: NM_001678
• Protein Refseq: NP_001669
• MIM: 182331
• UniProt ID: P14415
• Chromosome Location: 17p13.1
• Pathway: Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Basigin interactions, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Carbohydrate digestion and absorption, organism-specific biosystem
• Function: protein binding; sodium:potassium-exchanging ATPase activity