Recombinant Human ASIC1 Protein, GST-Tagged

• Cat.No.: ASIC1-151H
• Product Overview: Human ACCN2 full-length ORF ( NP_001086.2, 1 a.a. - 528 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
• Molecular Mass: 61.2 kDa
• AA Sequence: MGTEKESPEPDCQKQFQAAVSVIQNLPKNGSYRPSYEEMLRFYSYYKQATMGPCLVPRPGFWDPIGRYKWDAWNSLGKMSREEAMSAYITEMKLVAQKVIDTVPLGEVAEDMFGYFEPLYQVIPDMPRPPETFLRRVTGWKEQVVNGDVGAVSEPPCLPKEPAPPSPESHSPRDLDSEVFCDSLEQLEPELVWTEQRAASGGKRDPRNSPVPPTKKEGLRGSPPGPQELDVWLLGTVRALQESMQEVQARVQSLESMPRPPEQRPQPRPSARPWPLGLPGPALLFFLLWPFVVQWLFRMFRTQKR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ASIC1 acid sensing ion channel subunit 1 [ Homo sapiens (human) ]
• Official Symbol: ASIC1
• Synonyms: ASIC1; acid sensing ion channel subunit 1; Acid Sensing Ion Channel Subunit 1; Amiloride-Sensitive Cation Channel 2, Neuronal; Acid Sensing (Proton Gated) Ion Channel 1; Brain Sodium Channel 2; ACCN2; BNaC2; Cation Channel, Amiloride-Sensitive, Neuronal, 2; Acid-Sensing (Proton-Gated) Ion Channel 1; Acid-Sensing Ion Channel 1a Protein; Acid-Sensing Ion Channel 1; ASIC; acid-sensing ion channel 1; Cation channel, amiloride-sensitive, neuronal, 2; acid sensing (proton gated) ion channel 1; acid-sensing ion channel 1a protein; amiloride-sensitive cation channel 2, neuronal; brain sodium channel 2
• Gene ID: 41
• mRNA Refseq: NM_001095
• Protein Refseq: NP_001086
• MIM: 602866
• UniProt ID: P78348