Recombinant Human ARG1 Protein, His-tagged

• Cat.No.: ARG1-012H
• Product Overview: Active recombinant full length human C-terminal His-tagged ARG1 protein (1-322) was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 1-322
• Description: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
• Molecular Mass: 36 kDa
• Purity: ≥90% as determined by SDS-PAGE
• Stability: ≥ 1 year
• Storage: At -80 centigrade.
• Storage Buffer: 8 mM Phosphate buffer, pH 7.4, with 110 mM sodium chloride, 2.2 mM potassium chloride, and 20% glycerol

Gene Information

• Gene Name: ARG1 arginase 1 [ Homo sapiens (human) ]
• Official Symbol: ARG1
• Synonyms: ARG1; arginase 1; arginase-1; arginase, liver; liver-type arginase; type I arginase; EC 3.5.3.1
• Gene ID: 383
• mRNA Refseq: NM_000045
• Protein Refseq: NP_000036
• MIM: 608313
• UniProt ID: P05089