Recombinant Human AP1G2, His-tagged

• Cat.No.: AP1G2-3527H
• Product Overview: AP-1 complex subunit gamma-like 2 (AP1G2)

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 785
• Description: Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is compsed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. There are two alternatively spliced transcript variants of this gene encoding the same protein.
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of AP1G2 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: AP1G2 adaptor-related protein complex 1, gamma 2 subunit [ Homo sapiens ]
• Official Symbol: AP1G2
• Synonyms: G2AD
• Gene ID: 8906
• mRNA Refseq: NM_001282474
• Protein Refseq: NP_001269403
• MIM: 603534
• UniProt ID: O75843
• Chromosome Location: 14q11.2
• Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem
• Function: protein binding; protein transporter activity