Recombinant Human AOC1 protein, His-tagged

• Cat.No.: AOC1-668H
• Product Overview: Recombinant Human AOC1 aa. (Ala347~Asp466 (Accession# P19801)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 15.0kDa
• Protein length: Ala347~Asp466
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.8.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: AOC1 amine oxidase, copper containing 1 [ Homo sapiens (human) ]
• Official Symbol: AOC1
• Synonyms: AOC1; amine oxidase, copper containing 1; ABP; DAO; KAO; ABP1; DAO1; amiloride-sensitive amine oxidase [copper-containing]; amiloride binding protein 1 (amine oxidase (copper-containing)); amiloride-binding protein 1; amiloride-sensitive amine oxidase; amine oxidase copper domain-containing protein 1; diamine oxidase; histaminase; kidney amine oxidase
• Gene ID: 26
• mRNA Refseq: NM_001091.3
• Protein Refseq: NP_001082.2
• UniProt ID: P19801