Recombinant Human AOAH, GST-tagged

• Cat.No.: AOAH-150H
• Product Overview: Human AOAH full-length ORF ( NP_001628.1, 1 a.a. - 575 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.
• Source: Wheat germ
• Species: Human
• Tag: GST
• Molecular Mass: 91.5 kDa
• Protein length: 1 a.a. - 575 a.a.
• AA Sequence: MQSPWKILTVAPLFLLLSLQSSASPANDDQSRPSLSNGHTCVGCVLVVSVIEQLAQVHNSTVQASMERLCSYLPE KLFLKTTCYLVIDKFGSDIIKLLSADMNADVVCHTLEFCKQNTGQPLCHLYPLPKETWKFTLQKARQIVKKSPIL KYSRSGSDICSLPVLAKICQKIKLAMEQSVPFKDVDSDKYSVFPTLRGYHWRGRDCNDSDESVYPGRRPNNWDVH QDSNCNGIWGVDPKDGVPYEKKFCEGSQPRGIILLGDSAGAHFHISPEWITASQMSLNSFINLPTALTNELDWPQ LSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDV CSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSF LNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEP VDGFHPNEVALLLLADHFWKKVQLQWPQILGKENPFNPQIKQVFGDQGGH
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AOAH acyloxyacyl hydrolase (neutrophil) [ Homo sapiens (human) ]
• Official Symbol: AOAH
• Synonyms: AOAH; acyloxyacyl hydrolase (neutrophil); acyloxyacyl hydrolase; EC 3.1.1.77
• Gene ID: 313
• mRNA Refseq: NM_001637
• Protein Refseq: NP_001628
• MIM: 102593
• UniProt ID: P28039
• Chromosome Location: 7p14-p12
• Function: acyloxyacyl hydrolase activity; catalytic activity; lipoprotein lipase activity