Recombinant Human ANXA4, GST-tagged

• Cat.No.: ANXA4-9697H
• Product Overview: Recombinant Human ANXA4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 33-202a.a.
• Description: Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ANXA4 annexin A4 [ Homo sapiens ]
• Official Symbol: ANXA4
• Synonyms: ANXA4; annexin A4; ANX4; P32.5; PP4-X; PAP-II; annexin-4; protein II; endonexin I; lipocortin IV; chromobindin-4; 35-beta calcimedin; proliferation-inducing gene 28; proliferation-inducing protein 28; placental anticoagulant protein II; carbohydrate-binding protein p33/p41; annexin IV (placental anticoagulant protein II); PIG28; ZAP36; MGC75105; DKFZp686H02120
• Gene ID: 307
• mRNA Refseq: NM_001153
• Protein Refseq: NP_001144
• MIM: 106491
• UniProt ID: P09525
• Chromosome Location: 2p13.3
• Pathway: Prostaglandin Synthesis and Regulation, organism-specific biosystem
• Function: calcium ion binding; calcium ion binding; calcium-dependent phospholipid binding; calcium-dependent phospholipid binding; calcium-dependent phospholipid binding; phospholipase inhibitor activity