Recombinant Human Annexin A9, T7-tagged

• Cat.No.: ANXA9-69H
• Product Overview: Recombinant Human annexin 9 produced inE.coliis a non-glycosylated, polypeptide chain containing amino acids (1-338) and having a total molecular mass of 38.9 kDa. rhANXA9 contains T7 tag at N-terminus and is purified by proprietary chromatographic techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-338 a.a.
• Description: The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. The most striking feature of annexin 31 is a complete ablation of all four homologous type II calcium-binding sites in the conserved tetrad core. Although all 4 type II calcium-binding sites in annexin 31 contained amino acid substitutions that ablated their function, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.
• Physical Appearance: Sterile Filtered clear solution.
• Purity: Greater than 95.0% as determined by the analysis by reducing and non-reducing SDS-PAGE coomassie blue staining.
• Formulation: Recombinant Human Annexin-9 at a concentration of 0.1mg containing 10 mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3.
• Applications: •ELISA • MS• Western Blotting.
• Storage: RhAnnexin-9 although stable at 14°Cfor 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Gene Information

• Gene Name: ANXA9 annexin A9 [ Homo sapiens ]
• Synonyms: ANXA9; annexin A9; ANX31;Annexin A9; Annexin-9; Annexin-31; Annexin XXXI; OTTHUMP00000033027; Pemphaxin
• Gene ID: 8416
• mRNA Refseq: NM_003568
• Protein Refseq: NP_003559
• MIM: 603319
• UniProt ID: O76027
• Chromosome Location: 1q21
• Function: calcium ion binding; calcium-dependent phospholipid binding; acetylcholine receptor activity; phosphatidylserine binding; protein homodimerization activity