Recombinant Human ANGPTL3 Protein, FLAG-tagged

• Cat.No.: ANGPTL3-399H
• Product Overview: Fibrinogen-like domain of human ANGPTL3 (aa 224-460) is fused at the N-terminus to a FLAG®-tag was expressed in HEK293.

Specification

• Description: This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
• Source: HEK293
• Species: Human
• Tag: FLAG
• Form: Lyophilized
• Molecular Mass: ~35-38kDa
• Endotoxin: <0.01EU/μg purified protein (LAL test).
• Purity: ≥95% (SDS-PAGE)
• Stability: Stable for at least 6 months after receipt when stored at -20 centigrade.
  Working aliquots are stable for up to 3 months when stored at -20 centigrade.
• Storage: Short Term Storage: +4 centigrade
  Long Term Storage: -20 centigrade
• Concentration: After reconstitution
  for 10 μg size: 0.1 mg/mL
  for 50 μg size: 1 mg/mL
• Storage Buffer: Contains PBS.
• Reconstitution: 10 μg size: Reconstitute with 100 μL sterile water.
  50 μg size: Reconstitute with 50 μL sterile water.
• Shipping: BLUE ICE
• Protein length: 224-460 a.a.

Gene Information

• Gene Name: ANGPTL3 angiopoietin like 3 [ Homo sapiens (human) ]
• Official Symbol: ANGPTL3
• Synonyms: ANGPTL3; angiopoietin like 3; ANL3; ANG-5; FHBL2; ANGPT5; angiopoietin-related protein 3; angiopoietin 5
• Gene ID: 27329
• mRNA Refseq: NM_014495
• Protein Refseq: NP_055310
• MIM: 604774
• UniProt ID: Q9Y5C1