Recombinant Human ANAPC5 Protein, MYC/DDK-tagged

Cat.No. : ANAPC5-2085H
Product Overview : Recombinant human ANAPC5 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
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Species : Human
Source : HEK293
Tag : DDK&Myc
Description : This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008].
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 84.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name ANAPC5 anaphase promoting complex subunit 5 [ Homo sapiens ]
Official Symbol ANAPC5
Synonyms APC5; APC5
Gene ID 51433
mRNA Refseq NM_001137559
Protein Refseq NP_001131031
MIM 606948
UniProt ID Q9UJX4

Not For Human Consumption!

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