Recombinant Human ANAPC13, GST-tagged

• Cat.No.: ANAPC13-9636H
• Product Overview: Recombinant Human ANAPC13 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-74a.a.
• Description: This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ANAPC13 anaphase promoting complex subunit 13 [ Homo sapiens ]
• Official Symbol: ANAPC13
• Synonyms: ANAPC13; anaphase promoting complex subunit 13; anaphase-promoting complex subunit 13; APC13; DKFZP566D193; SWM1; cyclosome subunit 13; DKFZp566D193
• Gene ID: 25847
• mRNA Refseq: NM_001242374
• Protein Refseq: NP_001229303
• MIM: 614484
• UniProt ID: Q9BS18
• Chromosome Location: 3q22.1
• Pathway: APC/C complex, organism-specific biosystem; APC/C complex, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem