Recombinant Human ALS2 Protein, His-tagged
Cat.No. : | ALS2-166H |
Product Overview : | Recombinant Human ALS2, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Description : | The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Form : | 50mM Tris, 8M Urea, pH8.0. |
Molecular Mass : | 42.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name | ALS2 amyotrophic lateral sclerosis 2 (juvenile) [ Homo sapiens ] |
Official Symbol | ALS2 |
Synonyms | ALS2; amyotrophic lateral sclerosis 2 (juvenile); ALS2CR6, amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 6; alsin; amyotrophic lateral sclerosis 2 protein; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; ALSJ; PLSJ; IAHSP; ALS2CR6; FLJ31851; KIAA1563; MGC87187; |
Gene ID | 57679 |
mRNA Refseq | NM_001135745 |
Protein Refseq | NP_001129217 |
MIM | 606352 |
UniProt ID | Q96Q42 |
◆ Recombinant Proteins | ||
ALS2-1577M | Recombinant Mouse ALS2 Protein | +Inquiry |
ALS2-497H | Recombinant Human ALS2 Protein, GST-tagged | +Inquiry |
ALS2-642R | Recombinant Rat ALS2 Protein | +Inquiry |
ALS2-166H | Recombinant Human ALS2 Protein, His-tagged | +Inquiry |
ALS2-298R | Recombinant Rat ALS2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
ALS2-66HCL | Recombinant Human ALS2 cell lysate | +Inquiry |
Not For Human Consumption!
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