Recombinant Human ALDOC, His-tagged

• Cat.No.: ALDOC-26498TH
• Product Overview: Recombinant full length Human Aldolase C with an N terminal His tag; 384 amino acids with a predicted MWt 41.6kDa including tag.

Specification

• Description: This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.
• Protein length: 364 amino acids
• Conjugation: HIS
• Molecular Weight: 41.600kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 2mM DTT, 100mM Sodium chloride, pH 8
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSHMPHSYPALSA EQKKELSDIALRIVAPGKGI LAADESVGSM AKRLSQIGVE NTEENRRLYRQVLFSADDRV KKCIGGVIFF HETLYQKDDN GVPFVRTIQDKGIVVGIKVD KGVVPLAGTD GETTTQGLDG LSERCAQYKKDGADFAKWRC VLKISERTPS ALAILENANV LARYASICQQNGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HVYLEGTLLK PNMVTPGHAC PIKYTPEEIA MATVTALRRT VPPAVPGVTF LSGGQSEEEA SFNLNAINRC PLPRPWALTFSYGRALQASA LNAWRGQRDN AGAATEEFIK RAEVNGLAAQ GKYEGSGEDG GAAAQSLYIA NHAY
• Sequence Similarities: Belongs to the class I fructose-bisphosphate aldolase family.

Gene Information

• Gene Name: ALDOC aldolase C, fructose-bisphosphate [ Homo sapiens ]
• Official Symbol: ALDOC
• Synonyms: ALDOC; aldolase C, fructose-bisphosphate; fructose-bisphosphate aldolase C
• Gene ID: 230
• mRNA Refseq: NM_005165
• Protein Refseq: NP_005156
• MIM: 103870
• Uniprot ID: P09972
• Chromosome Location: 17
• Pathway: Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Gluconeogenesis, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, organism-specific biosystem
• Function: cytoskeletal protein binding; fructose-bisphosphate aldolase activity; lyase activity; protein binding