Recombinant Human AK5, His-tagged

• Cat.No.: AK5-26526TH
• Product Overview: Recombinant full-length Human AK5 with a N terminal His tag. 586 amino acids with a predicted MWt 65.9 kDa including tag.

Specification

• Description: This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
• Protein length: 562 amino acids
• Conjugation: HIS
• Molecular Weight: 65.900kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Brain specific.
• Form: Liquid
• Purity: by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 20% Glycerol, 0.02% DTT
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMGSHMNTNDAKEYMARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPGNSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF
• Sequence Similarities: Belongs to the adenylate kinase family.

Gene Information

• Gene Name: AK5 adenylate kinase 5 [ Homo sapiens ]
• Official Symbol: AK5
• Synonyms: AK5; adenylate kinase 5; adenylate kinase isoenzyme 5
• Gene ID: 26289
• mRNA Refseq: NM_012093
• Protein Refseq: NP_036225
• MIM: 608009
• Uniprot ID: Q9Y6K8
• Chromosome Location: 1p31
• Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem
• Function: ATP binding; adenylate kinase activity; cAMP-dependent protein kinase regulator activity; nucleoside kinase activity; nucleotide binding