Recombinant Human AGXT, MYC/DDK-tagged

• Cat.No.: AGXT-84837H
• Product Overview: Recombinant Human AGXT, fused with C-terminal MYC/DDK, was expressed in HEK293.

Specification

• Description: This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 42.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: AGXT alanine-glyoxylate aminotransferase [ Homo sapiens (human) ]
• Official Symbol: AGXT
• Synonyms: AGXT; AGT; PH1; SPT; AGT1; SPAT; TLH6; AGXT1; alanine-glyoxylate aminotransferase; serine--pyruvate aminotransferase; serine-pyruvate aminotransferase; serine:pyruvate aminotransferase; alanine--glyoxylate aminotransferase; L-alanine: glyoxylate aminotransferase 1; hepatic peroxisomal alanine:glyoxylate aminotransferase; NP_000021.1; EC 2.6.1.44; EC 2.6.1.51
• Gene ID: 189
• mRNA Refseq: NM_000030
• Protein Refseq: NP_000021
• MIM: 604285
• UniProt ID: P21549
• Chromosome Location: 2q37.3
• Pathway: Alanine and aspartate metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism
• Function: alanine-glyoxylate transaminase activity; protein homodimerization activity; pyridoxal phosphate binding