Recombinant Human ADRM1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ADRM1-664H
• Product Overview: ADRM1 MS Standard C13 and N15-labeled recombinant protein (NP_008933) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 42.15 kDa
• AA Sequence: MTTSGALFPSLVPGSRGASNKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNNPPMPGALGASGSSGHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLGSSGPPGSSSSSSSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPSSGNGASTAASPTQPIQLSDLQSILATMNVPAGPAGGQQVDLASVLTPEIMAPILANADVQERLLPYLPSGESLPQTADEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNNAKPEQKEGDTKDKKDEEEDMSLDTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ADRM1 adhesion regulating molecule 1 [ Homo sapiens (human) ]
• Official Symbol: ADRM1
• Synonyms: ADRM1; adhesion regulating molecule 1; proteasomal ubiquitin receptor ADRM1; ARM1; GP110; Rpn13; ARM-1; hRpn13; rpn13 homolog; M(r) 110,000 surface antigen; adhesion-regulating molecule 1; regulatory particle non-ATPase 13; 110 kDa cell membrane glycoprotein; proteasome regulatory particle non-ATPase 13; MGC29536
• Gene ID: 11047
• mRNA Refseq: NM_007002
• Protein Refseq: NP_008933
• MIM: 610650
• UniProt ID: Q16186