Recombinant Human ACVR2A cell lysate, Myc/DDK tag

• Cat.No.: ACVR2A-3097HCL
• Product Overview: Transient overexpression lysate of activin A receptor, type IIA (ACVR2A) with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag
• Protein Length: 1-513aa
• Description: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.
• Molecular Mass: 57.85 kDa
• Usage: 1 vial of 100 μg gene specific transient over-expression cell lysate in RIPA buffer
  1 vial of 100 μg empty vector transfected control cell lysate in RIPA buffer
  1 vial of 250 μL 2×SDS Sample Buffer (4% SDS, 125mM Tris-HCl pH6.8, 10% Glycerol, 0.002% Bromphenol blue, 100mM DTT)
• Stability: Lysate samples are stable for 12 months from the date of receipt when stored at -80 centigrade.
• Storage: Upon receiving, store the sample at -80 centigrade. Also after dilution, the protein sample should be aliquoted and stored at -80 centigrade for long term storage. Avoid repeated freeze-thaw cycles.
• Dilutions: Lysate samples can be diluted with 2×SDS Sample Buffer provided.
• Shipping: The lysate is shipped with dry ice.

Gene Information

• Gene Name: ACVR2A activin A receptor type 2A [ Homo sapiens (human) ]
• Official Symbol: ACVR2A
• Synonyms: ACVR2A; activin A receptor type 2A; ACVR2; ACTRII; activin receptor type-2A; activin A receptor, type IIA; EC 2.7.11.30
• Gene ID: 92
• mRNA Refseq: NM_001616
• Protein Refseq: NP_001607
• MIM: 102581
• UniProt ID: P27037