Recombinant Human ACKR2 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ACKR2-1629H |
Product Overview : | CCBP2 MS Standard C13 and N15-labeled recombinant protein (NP_001287) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. |
Molecular Mass : | 43.4 kDa |
AA Sequence : | MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLGLSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKMVSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPDMVFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRLRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEMTGMNDLGERQSENYPNKEDVGNKSATRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name | ACKR2 atypical chemokine receptor 2 [ Homo sapiens (human) ] |
Official Symbol | ACKR2 |
Synonyms | ACKR2; atypical chemokine receptor 2; D6; hD6; CCR9; CCBP2; CCR10; CMKBR9; atypical chemokine receptor 2; C-C chemokine receptor D6; CC-chemokine-binding receptor JAB61; chemokine (C-C motif) receptor 9; chemokine (C-C) receptor 9; chemokine receptor CCR-10; chemokine receptor CCR-9; chemokine receptor D6; chemokine-binding protein 2; chemokine-binding protein D6 |
Gene ID | 1238 |
mRNA Refseq | NM_001296 |
Protein Refseq | NP_001287 |
MIM | 602648 |
UniProt ID | O00590 |
Not For Human Consumption!
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