Recombinant Human ACE2 Protein (ECD, AA 20-707), C-Avi/His-Tagged, Biotinylated
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- Specification
- Gene Information
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| Species : | Human |
| Source : | HEK293 |
| Tag : | Avi&His |
| Protein Length : | AA 20-707 |
| Description : | The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2, the latter is the causative agent of coronavirus disease-2019 (COVID-19). Multiple splice variants have been found for this gene and the dACE2 (or MIRb-ACE2) splice variant has been found to be interferon inducible. |
| Form : | Liquid |
| AA Sequence : | MTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMS |
| Purity : | > 80% as determined by SDS-PAGE |
| Storage : | Stored and shipped at -80 centigrade |
| Storage Buffer : | PBS, pH 7.4 |
| Gene Name | ACE2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 [ Homo sapiens ] |
| Official Symbol | ACE2 |
| Synonyms | ACE2; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme 2; metalloprotease MPROT15; ACE-related carboxypeptidase; angiotensin I converting enzyme 2; angiotensin-converting enzyme homolog; ACEH |
| Gene ID | 59272 |
| mRNA Refseq | NM_021804 |
| Protein Refseq | NP_068576 |
| MIM | 300335 |
| UniProt ID | Q9BYF1 |
| ◆ Recombinant Proteins | ||
| ACE2-089H | Recombinant Human ACE2 Protein, DYKDDDDK-tagged | +Inquiry |
| ACE2-051H | Active Recombinant Human ACE2 protein, His/Avi-tagged, Biotinylated | +Inquiry |
| ACE2-0078H | Recombinant Human ACE2 Protein (Leu392-Ser740), His-tagged | +Inquiry |
| ACE2-370H | Recombinant Human ACE2 Protein (Gln18-Ser740), C-mFc-tagged | +Inquiry |
| ACE2-5060H | Recombinant Human ACE2 Protein (Ser19-Ser740), C-His tagged | +Inquiry |
| ◆ Cell & Tissue Lysates | ||
| ACE2-887CCL | Recombinant Cynomolgus ACE2 cell lysate | +Inquiry |
| ACE2-3100HCL | Recombinant Human ACE2 cell lysate | +Inquiry |
| ACE2-2085MCL | Recombinant Mouse ACE2 cell lysate | +Inquiry |
| ACE2-1851RCL | Recombinant Rat ACE2 cell lysate | +Inquiry |
Not For Human Consumption!
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