Recombinant Human ABI3 Protein, MYC/DDK-tagged

• Cat.No.: ABI3-675H
• Product Overview: Recombinant human ABI3 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 38.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ABI family member 3[ Homo sapiens ]
• Official Symbol: ABI3
• Synonyms: NESH; SSH3BP3
• Gene ID: 51225
• mRNA Refseq: NM_001135186.1
• Protein Refseq: NP_001128658.1
• MIM: 606363
• UniProt ID: Q9P2A4