Recombinant Human ABCD4 Protein, C-Myc/DDK-Tagged

• Cat.No.: ABCD4-01H
• Product Overview: Recombinant Human ABCD4 Protein, C-Myc/DDK-Tagged was expressed in HEK293T cell.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants.
• Molecular Mass: 68.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80°C.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Cytogenetics: 14q24.3
• Refseq Size: 3157
• Refseq ORF: 1818
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: ABCD4 ATP binding cassette subfamily D member 4 [ Homo sapiens (human) ]
• Official Symbol: ABCD4
• Synonyms: ABC41; EST352188; MAHCJ; P70R; P79R; PMP69; PXMP1L
• Gene ID: 5826
• mRNA Refseq: NM_005050.4
• Protein Refseq: NP_005041.1
• MIM: 603214
• UniProt ID: O14678