Recombinant HRSV G protein, His-tagged

Cat.No. : G-99V
Product Overview : Recombinant HRSV G protein(His 67 - Arg 297) fused with His tag at C-terminal was expressed in HEK293.
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Species : HRSV
Source : HEK293
Tag : His
Protein Length : His 67 - Arg 297
Description : Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. Human respiratory syncytial virus A (strain Long) major surface glycoprotein G (RSV-G), a member of the pneumoviruses glycoprotein G family, is also known as attachment glycoprotein G and membrane-bound glycoprotein (mG), which contains a linear heparin binding domain essential for virus attachment to the host. Concretely speaking, RSV-G can attache the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Furthermore, RSV-G can also interact with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, RSV-G lacks both neuraminidase and hemagglutinating activities.
Predicted N Terminal : His 67
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Molecular Mass : Has a calculated MW of 26.2 kDa. DTT-reduced Protein migrates as 60-94 kDa in SDS-PAGE due to glycosylation.
Endotoxin : Less than 1.0 EU per μg of the rh RSV-G by the LAL method.
Purity : >90% as determined by SDS-PAGE.
Storage : Avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade).
Gene Name G G [ Human respiratory syncytial virus ]
Official Symbol G
Synonyms G; attachment glycoprotein
Gene ID 1489824
Protein Refseq NP_056862
UniProt ID O36633

Not For Human Consumption!

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