Recombinant HRSV G protein, His-tagged
Cat.No. : | G-99V |
Product Overview : | Recombinant HRSV G protein(His 67 - Arg 297) fused with His tag at C-terminal was expressed in HEK293. |
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Species : | HRSV |
Source : | HEK293 |
Tag : | His |
Protein Length : | His 67 - Arg 297 |
Description : | Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. Human respiratory syncytial virus A (strain Long) major surface glycoprotein G (RSV-G), a member of the pneumoviruses glycoprotein G family, is also known as attachment glycoprotein G and membrane-bound glycoprotein (mG), which contains a linear heparin binding domain essential for virus attachment to the host. Concretely speaking, RSV-G can attache the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Furthermore, RSV-G can also interact with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, RSV-G lacks both neuraminidase and hemagglutinating activities. |
Predicted N Terminal : | His 67 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Molecular Mass : | Has a calculated MW of 26.2 kDa. DTT-reduced Protein migrates as 60-94 kDa in SDS-PAGE due to glycosylation. |
Endotoxin : | Less than 1.0 EU per μg of the rh RSV-G by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade). |
Gene Name | G G [ Human respiratory syncytial virus ] |
Official Symbol | G |
Synonyms | G; attachment glycoprotein |
Gene ID | 1489824 |
Protein Refseq | NP_056862 |
UniProt ID | O36633 |
Not For Human Consumption!
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