Recombinant HIV1 Envelope gp120/gp41 Fusion Protein

• Cat.No.: gp120/gp41-42H
• Product Overview: This recombinant protein contains immunodominant regions of HIV-1 gp120 and gp41 proteins with a MW of 47 kDa. It is recognized by positive samples in ELISA tests.

Specification

• Species: HIV
• Source: E.coli
• Description: gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
• Form: Affinity purified, liquid
• Molecular Mass: 47 kDa
• Purity: >95% pure by SDS-PAGE
• Applications: Suitable for use in ELISA, Lateral Flow, WB, and other immune tests.
• Storage: Upon receipt, store at 2-8 centigrade.
• Storage Buffer: Borax buffer, pH 9.2
• Preservative: 0.1% ProClin 300

Gene Information

• Synonyms: Glycoprotein 120; gp120; SU; Surface protein; Env; Glycoprotein 41; gp41; Human Immunodeficiency Virus 1; TM; Transmembrane protein