Recombinant Goat TLR4 Protein, His-tagged

• Cat.No.: TLR4-421G
• Product Overview: Recombinant Goat TLR4 Protein (Trp26-Leu253) with N-His tag was expressed in E. coli.

Specification

• Species: Goat
• Source: E.coli
• Tag: His
• Protein Length: Trp26-Leu253
• Description: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved histidines and are, therefore, species-specific.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29.6 kDa
  Accurate Molecular Mass: 32 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: TLR4 toll-like receptor 4 [ Capra hircus (goat) ]
• Official Symbol: TLR4
• Synonyms: TLR4; toll-like receptor 4; TLR 4; EC 3.2.2.6
• Gene ID: 100860955
• mRNA Refseq: NM_001285574
• Protein Refseq: NP_001272503
• UniProt ID: E5FXB8