Recombinant Full Length Mouse Ptges Protein, Myc/DDK-tagged

• Cat.No.: Ptges-5220M
• Product Overview: Purified recombinant protein of mouse full-length prostaglandin E synthase (Ptges), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli. Plays a key role in inflammation response, fever and pain. Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2. In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively.
• Molecular Mass: 17.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ptges prostaglandin E synthase [ Mus musculus (house mouse) ]
• Official Symbol: Ptges
• Synonyms: PTGES; prostaglandin E synthase; microsomal prostaglandin E synthase 1; Pges; mPGES; mPGES-1; D2Ertd369e; 2410099E23Rik
• Gene ID: 64292
• mRNA Refseq: NM_022415
• Protein Refseq: NP_071860
• UniProt ID: Q9JM51